首页|血常规多参数联合检测对大细胞性贫血与正常细胞性贫血的鉴别诊断

血常规多参数联合检测对大细胞性贫血与正常细胞性贫血的鉴别诊断

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目的 研究血常规多参数联合检测对大细胞性贫血与正常细胞性贫血的鉴别诊断。方法 选取2021年1月至2023年1月我院收治的72例贫血患者作为贫血组,另取同期健康体检人员40名作为对照组。比较两组的各项血常规参数水平;比较大细胞性贫血与正常细胞性贫血患者的各项血常规参数水平;分析血常规多参数联合检测鉴别诊断大细胞性贫血与正常细胞性贫血的效能。结果 贫血组的红细胞计数(RBC)、血红蛋白(Hb)水平及红细胞平均体积(MCV)、平均红细胞血红蛋白含量(MCH)均低于对照组,红细胞分布宽度(RDW)大于对照组,差异具有统计学意义(P<0。05)。大细胞性贫血患者的RBC、Hb水平均低于正常细胞性贫血患者,RDW、MCV均高于正常细胞性贫血患者,差异具有统计学意义(P<0。05)。将病理结果视为金标准,RBC、Hb、RDW、MCV联合检测诊断大细胞性贫血的灵敏度、特异度、准确度为95。12%、93。55%、94。44%,均高于RBC、Hb、RDW、MCV单独诊断(P<0。05)。结论 RBC、Hb、MCV、MCH在贫血患者中明显降低,RDW明显增大。其中血常规多参数RBC、Hb、RDW、MCV联合检测在大细胞性贫血与正常细胞性贫血的鉴别诊断中应用及推广价值较高,可为贫血患者的早期诊治提供指导依据。
Differential diagnosis of macrocytic anemia and normal cell anemia by combined detection of blood routine multi-parameter
Objective To study the differential diagnosis of macrocytic anemia and normal cell anemia by combined detection of blood routine multi-parameter.Methods A total of 72 patients with anemia admitted in our hospital from January 2021 to January 2023 were selected as anemia group,and 40 healthy people who underwent physical examination during the same period were selected as control group.The blood routine parameters of the two groups were compared;the levels of blood routine parameters in patients with macrocytic anemia and normal cell anemia were compared;the efficacy of blood routine multi-parameter combined detection in the differential diagnosis of macrocytic anemia and normal cell anemia were analyzed.Results The red blood cell(RBC),hemoglobin(Hb)levels and mean corpuscular volume(MCV),mean concentration hemoglobin(MCH)in the anemia group were lower than those in the control group,and the red cell distribution width(RDW)was larger than that in the control group,and the differences were statistically significant(P<0.05).The levels of RBC and Hb in patients with macrocytic anemia were lower than those in patients with normal cell anemia,and the RDW and MCV were higher than those in patients with normal cell anemia,and the differences were statistically significant(P<0.05).The pathological results were taken as the gold standard,the sensitivity,specificity and accuracy of combined detection of RBC,Hb,RDW and MCV in the diagnosis of large cell anemia were 95.12%,93.55%and 94.44%respectively,which were higher than those of RBC,Hb,RDW and MCV alone(P<0.05).Conclusion RBC,Hb,MCV and MCH are significantly reduced in patients with anemia,while RDW is significantly increased.The combined detection of blood routine multi-parameter RBC,Hb,RDW and MCV has high application and promotion value in the differential diagnosis of macrocytic anemia and normal cell anemia,which can provide guidance for the early diagnosis and treatment of anemia patients.

normal cell anemiamacrocytic anemiablood routinedifferential diagnosis

刘锦、杨扬

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西安大兴医院输血科,陕西西安,710016

正常细胞性贫血 大细胞性贫血 血常规 鉴别诊断

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(36)