Detection of immunoglobulin levels and analysis of allergen in children with allergic purpura
Objective To analyze the immunoglobulin levels and allergic sources of allergic purpura in children.Methods A total of 100 children with allergic purpura admitted in our hospital from January 2019 to January 2023 were selected as allergic group,and 100 volunteer children who came to the hospital for physical examination during the same period were selected as control group.Serum specific immunoglobulin G,A,M,D and E levels were detected and compared between the two groups;the positive detection rate of inhalation and food allergens in the allergic group were analyzed.Results The levels of serum specific immunoglobulin G,A,M,D and E in the allergic group were significantly higher than those in the control group,and the differences were statistically significant(P＜0.05).The total positive detection rate of inhaled allergens in the allergic group was 89.00％;pollen,willow catkins,dust,mites and animal dander were common inhalation allergens.The total positive detection rate of food allergens in the allergic group was 86.00％;crabs,crayfish,scallops,mango and pineapple were common food allergens.After treatment,the levels of serum specific immunoglobulin G,A,M,D and E in the allergic group were significantly lower than those before treatment,and the differences were statistically significant(P＜0.05).Conclusion The detection of allergens has a high application value for children with allergic purpura,and targeted treatment can be adopted by quickly identifying allergens,so as to ensure the therapeutic effect and healthy development of children.
childrenallergic purpuraallergen detectionserum specific immunoglobulin
万方数据
维普
