Effect of Yiqi Bushen prescription combined with progesterone in the treatment of threatened abortion(kidney deficiency syndrome)and its influences on sHLA-G and IL-17 levels
Objective To explore the effect of Yiqi Bushen prescription combined with progesterone in the treatment of threatened abortion(kidney deficiency syndrome)and its influences on the levels of soluble human leukocyte antigen-G(sHLA-G)and interleukin-17(IL-17).Methods A total of 80 pregnant women with threatened abortion(kidney deficiency syndrome)admitted from January 2020 to October 2022 were selected as the research objects.According to the random number table method,the pregnant women were divided into control group and observation group,with 40 cases in each group.The control group was treated with progesterone,and the observation group was treated with Yiqi Bushen prescription on the basis of the control group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was 95.00％,which was higher than 80.00％in the control group,and the difference was statistically significant(P＜0.05).After treatment,the level of sHLA-G in the observation group was higher than that in the control group,and the level of IL-17 was lower than that in the control group,and the differences were statistically significant(P＜0.05).After treatment,the levels of β-human chorionic gonadotropin(β-HCG),progesterone(P)and estradiol(E2)in the observation group were higher than those in the control group,and the differences were statistically significant(P＜0.05).The vaginal bleeding stop time,lumbago relief time and abdominal pain stop time in the observation group were shorter than those in the control group,and the full-term delivery rate was higher than that in the control group,and the differences were statistically significant(P＜0.05).Conclusion Yiqi Bushen prescription combined with progesterone in the treatment of threatened abortion(kidney deficiency syndrome)pregnant women can regulate sHLA-G,IL-17 and hormone levels,shorten the vaginal bleeding stop time,lumbago relief time and abdominal pain stop time,improve the effect of fetal protection and full-term delivery rate,which is worthy of promotion.
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