Objective To explore the effects of comorbidity of chronic diseases on depression and anxiety a-mong the elderly aged 65 and above in Haidian District,Beijing.Methods A total of 3 600 people aged 65 and above in 15 subdistricts,Haidian District were recruited.A face-to-face survey was conducted among the elderly people with a self-designed questionnaire on chronic disease.The Geriatric Depression Scale(GDS-15)and the Self-rating Anxiety Scale(SAS)were used to assess depression and anxiety.Logistic regression was used to analyze the influencing factors.Results Of the 3 387 participants with valid information,1 218(35.96%)were identified as having comorbidity of chronic diseases,depression and anxiety were reported by 573(16.92%)and 367(10.84%)respectively.Depression and anxiety were detected in 268(22.00%)and 207(17.00%)of the elderly with chronic disease comorbidities,while depression and anxiety were detected in 305(14.06%)and 160(7.38%)of the non-comorbidities.The positive rates of depression and anxiety were 1.56 times and 2.30 times of those of non-comorbidity,respectively.Multivariate lo-gistic regression analysis showed that the elderly with comorbidity of chronic diseases,in contrast to those without,were at an increased risk of depression(OR=3.051,95%CI:1.993-4.673)and anxiety(OR=5.196,95%CI:3.276-8.240).Hypertension and osteoarthropathy comorbidities were risk factors for depression(OR=2.276,95%CI:1.641-3.157).Hypertension and cardiovascular disease,hypertension and osteoarthropathy comorbidities were risk factors for anxiety(OR=1.889,95%CI:1.285-2.777;OR=3.102,95%CI:2.150-4.476).Conclusion Comor-bidity of chronic diseases increase the risk of depression and anxiety among the elderly people.