中国临床保健杂志2024，Vol.27Issue(2) ：273-276.DOI:10.3969/J.issn.1672-6790.2024.02.026

卵巢-附件影像报告和数据系统分类联合血清学检查对卵巢-附件肿瘤的诊断价值

Diagnostic value of ultrasound Ovarian-Adnexal Reporting and Data System classification combined with serum carbohydrate antigen 125 and human epididymis protein 4 for ovarian-adnexal masses

冯景 任永凤 李健 马利亚 李晓雪
中国临床保健杂志2024，Vol.27Issue(2) ：273-276.DOI:10.3969/J.issn.1672-6790.2024.02.026
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  • 万方数据

卵巢-附件影像报告和数据系统分类联合血清学检查对卵巢-附件肿瘤的诊断价值

Diagnostic value of ultrasound Ovarian-Adnexal Reporting and Data System classification combined with serum carbohydrate antigen 125 and human epididymis protein 4 for ovarian-adnexal masses

冯景 1任永凤 1李健 1马利亚 1李晓雪1
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作者信息

  • 1. 安徽医科大学附属亳州医院(亳州市人民医院)超声科,亳州 236800
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摘要

目的 探讨卵巢-附件影像报告和数据系统(O-RADS)分类联合血清糖类抗原125(CA125)及人附睾分泌蛋白4(HE4)对卵巢-附件肿瘤的诊断价值.方法 回顾性分析安徽医科大学附属亳州医院(亳州市人民医院)收治并病理确诊的卵巢-附件肿瘤患者90例,以病理结果为金标准,分析超声O-RADS分类、血清CA125、HE4对卵巢-附件恶性肿瘤的检出率.运用受试者工作特征(ROC)曲线分析O-RADS分类、CA125、HE4及三者联合应用对卵巢-附件肿瘤的诊断效能.结果 90例卵巢-附件肿瘤中,良性61例,恶性29例.O-RADS分类中2、3、4、5类对恶性肿瘤的检出率依次增高,与良性肿瘤比较,差异有统计学意义(P＜0.001),血清CA125、HE4对恶性肿瘤的检出率分别为72.00％、70.37％,与良性肿瘤比较,差异有统计学意义(P均＜0.001).O-RADS分类、CA125、HE4及三者联合诊断卵巢-附件肿瘤的曲线下面积(AUC)分别为0.783、0.753、0.762、0.909,联合诊断AUC高于任一单独诊断技术(P均＜0.05).结论 超声O-RADS分类联合血清CA125、HE4有助于提高卵巢-附件肿瘤的诊断效能.

Abstract

Objective To explore the diagnostic value of Ovarian-Adnexal Reporting and Data System(O-RADS)combined with serum carbohydrate antigen 125(CA125)and human epididymis protein 4(HE4)for ovari-an-adnexal masses.Methods A total of 90 cases with ovarian-adnexal masses admitted to the Affiliated Bozhou Hospi-tal of Anhui Medical University(the People's Hospital of Bozhou)were retrospectively analyzed and pathologically diag-nosed.Taking the pathological results as the gold standard,the detection rates of malignant ovarian-adnexal masses were analyzed by ultrasound O-RADS classification,serum CA125 and HE4.The diagnostic efficacy of O-RADS classifica-tion,serum CA125,HE4,and the combination of the three on the diagnosis of ovarian-adnexal masses was analyzed through ROC curve.Results Among 90 cases with ovarian-adnexal masses,61 were benign and 29 were malignant.The detection rates of malignant masses with O-RADS 2,3,4,5 classifications increased sequentially,with the statistically significant differences compared with benign masses(P＜0.001).The detection rates of malignant masses in serum CA125 and HE4 were 72.00％and 70.37％,respectively,with the statistically significant differences compared with be-nign masses(all P＜0.001).The area under the curve(AUC)of O-RADS classification,serum CA1 25,HE4,and the joint diagnosis of ovarian-adnexal masses was 0.783,0.753,0.762,and 0.909,respectively.The combination of the three was higher than any one of the individual diagnostic techniques(all P＜0.05).Conclusions Ultrasound O-RADS classification combined with CA125,HE4 can improve the diagnostic efficiency of ovarian-adnexal masses.

关键词

卵巢肿瘤/诊断技术,妇产科/CA-125抗原/附睾分泌蛋白质类/超声检查,多普勒,彩色

Key words

Ovarian neoplasms/Diagnostic techniques,obstetrical and gynecological/CA-125 antigen/Epididy-mal secretory proteins/Ultrasonography,doppler,color

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基金项目

安徽医科大学项目(2022xkj231)

出版年

2024
中国临床保健杂志
卫生部北京医院 安徽省保健委员会

中国临床保健杂志

CSTPCD
影响因子：0.931
ISSN：1672-6790
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