Objective To investigate the sarcopenia prevalence and associated factors in the hospitalized older patients.Methods A total of 309 older inpatients eligible for inclusion in People's Hospital of Xinjiang Uygur Autono-mous region from May 2022 to April 2023 were selected as the study objects.Their demographic data,chronic diseases and laboratory test indicators were collected.The prevalence of depression assessed by the Depression Screening Scale,anxiety assessed by the Generalized Self-Rating Anxiety Scale,pain assessed by the International Association for the Study of Pain,sleep assessed by the Athens Insomnia Scale,nutrition assessed by the Mininutrition Assessment Scale,and cognitive function assessed by the Simple Intelligent Mental State Examination Scale.Sarcopenia was diagnosed ac-cording to the diagnostic criteria of the Asian Sarcopenia Working Group in 2019,and the patients were divided into the sarcopenia group(49 cases)and the non-sarcopenia group(260 cases).Binary logistic regression analysis was per-formed to identify the factors associated with sarcopenia.Results The prevalence of sarcopenia was 15.9%in 309 ol-der inpatients,And the prevalence of sarcopenia in patients ≥80 years old was 33.7%.There were significant differ-ences in age,BMI,nutritional status,cognitive function,exercise,hypertension,coronary heart disease,chronic heart fail-ure,chronic obstructive pulmonary disease,Alb,Hb,eGFR,TG,TC and LDL-C between the sarcopenia group and the non-sarcopenia group(P<0.05).Binary logistic regression analysis results showed:lack of exercise(OR=3.207,95%CI:1.370-7.509)and coronary heart disease(OR=3.677,95%CI:1.497-9.029)were the risk factors for sar-copenia in older hospitalized patients(P<0.05).Increased BMI(OR=0.732,95%CI:0.617-0.869)was a protective factor for sarcopenia in older hospitalized patients(P<0.05).Conclusions The prevalence of sarcopenia is higher in hospitalized elderly patients.The risk of sarcopenia in hospitalized older patients with low B MI,lack of exercise and coro-nary heart disease is increased.