Objective To analyze the status and risk factors of reduction loss in elderly patients with distal ra-dius fractures after plate internal fixation through a palmar approach.Methods Retrospective analysis of medical re-cords of 80 elderly patients with distal radius fractures admitted to Xianyang First People's Hospital from January 2018 to December 2022.The patients were grouped based on whether there was reduction loss after operation.Univariate analysis and multivariate logistic regression analysis were conducted to identify the influencing factors of postoperative reduction loss.Results Among the 80 elderly patients with distal radius fractures,there were 24(30.00%)patients with postop-erative reduction loss and 56(70.00%)patients without.There were statistically significant differences between the two groups in terms of age,AO classification of fracture,time from fracture to operation,osteoporosis status,distance from dis-tal radius to distal screw,and start time of postoperative exercise(P<0.05).Multivariate logistic regression analysis showed that age,AO classification of fracture,time from fracture to operation,osteoporosis,and distance from distal radi-us to distal screw were influencing factors of reduction loss in elderly patients with distal radius fractures after plate in-ternal fixation through a palmar approach(P<0.05).Conclusions The incidence of reduction loss is relatively higher in elderly patients with distal radius fractures who have undergone plate internal fixation through a palmar approach.Age,AO classification of fracture,time from fracture to operation,osteoporosis,and distance from distal radius to distal screw are influencing factors of reduction loss.