首页|纤维蛋白原与白蛋白比值及CHADS2评分与冠状动脉慢性完全闭塞性病变的相关性研究

纤维蛋白原与白蛋白比值及CHADS2评分与冠状动脉慢性完全闭塞性病变的相关性研究

The correlation between fibrinogen to albumin ratio and CHADS2 scores with coronary chronic total occlusion

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目的 探讨纤维蛋白原与白蛋白比值(FAR)及CHADS2评分与冠状动脉慢性完全闭塞性病变(CTO)的相关性.方法 回顾性分析2015年7月至2023年12月于安徽医科大学第二附属医院老年心血管内科行冠状动脉造影术(CAG)检查确诊的244例冠心病患者病历资料,根据CAG结果将其分为CTO组(142例)和非CTO组(102例).根据Gensini积分取三分位数分组,将其分为低积分组(82例)、中积分组(82例)和高积分组(80例).结果 CTO和非CTO患者间年龄、高血压、心力衰竭、脑血管事件、吸烟、血红蛋白、白蛋白、尿素氮、纤维蛋白原、FAR、CHADS2评分及Gensini积分比较,差异有统计学意义(P<0.05).多因素logistic回归分析结果显示,吸烟、FAR及CHADS2评分与CTO相关(P<0.05).各积分组患者间年龄、心力衰竭比例、吸烟比例、白蛋白、总胆固醇、纤维蛋白原、FAR、CHADS2评分及CTO比例比较,差异均有统计学意义(均P<0.05)o Spearman相关分析显示,FAR和CHADS2评分与Gensini积分均呈正相关(P<0.05).结论 FAR及CHADS2评分与CTO的发生独立相关,对于患者术前冠状动脉病变严重程度的评估有一定的指导意义.
Objective To investigate the correlation between fibrinogen to albumin ratio(FAR)and CHADS2 scores in patients with coronary chronic total occlusion(CTO).Methods Two hundred and forty-four patients who un-derwent coronary angiography(CAG)in the Department of Geriatric Cardiology at the Second Affiliated Hospital of An-hui Medical University from July 2015 to December 2023 were included with coronary artery angiography,which were classified into CTO(n=142)and non-CTO(n=102).The tertiles were divided into three groups according to Gensini score,including low-score group(n=82),medium-score group(n=82)and high-score group(n=80).Result The age,the incidence of hypertension,heart failure,cerebrovascularevents,smoking,hemoglobin,albumin,urea nitrogen,fi-brinogen,FAR,CHADS2 scores and Gensini score were significantly different between in CTO group and non-CTO group(P<0.05).Multivariate logistic regression analysis showed that smoking,FAR and CHADS2 score were associated with CTO(P<0.05).There were significant differences in age,heart failure ratio,smoking ratio,albumin,total cholesterol,fibrinogen,FAR,CHADS2 score,and CTO ratio among different score groups(P<0.05).Correlation analysis showed that FAR and Gensini score,CHADS2 scores and Gensini score were statistically significant(P<0.05).Conclusions FAR and CHADS2 scores are independently associated with the occurrence of CTO and there is a correlation between FAR and CHADS2 scores and the severity of CTO,which have some implications for the assessment of preoperative coro-nary severity.

Coronary diseaseAngiocardiographyFibrinogenAlbuminsRoot cause analysis

杨二丽、张晶晶、朱华良、赵宇飞、祝小霞、黄正

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安徽医科大学第二附属医院老年心血管内科,合肥 230601

安徽医科大学第二附属医院心血管内科,合肥 230601

冠心病 心血管造影术 纤维蛋白原 白蛋白类 影响因素分析

2024

中国临床保健杂志
卫生部北京医院 安徽省保健委员会

中国临床保健杂志

CSTPCD
影响因子:0.931
ISSN:1672-6790
年,卷(期):2024.27(4)