Objective To explore the clinical characteristics and influencing factors of type 2 diabetes mellitus on the outcome of hospitalized elderly patients with COVID-19.Methods The medical records of 129 elderly patients diagnosed with COVID-19 who were admitted to the First Affiliated Hospital of the University of Science and Technology of China(Anhui Provincial Hospital)from December 2022 to March 2023 were selected.According to the presence or absence of type 2 diabetes,they were divided into diabetes(DM)group(70 cases)and non-diabetes(NDM)group(59 cases).The patient's clinical data were obtained and analyzed through clinical electronic medical records.Results Compared with NDM group,DM group had a higher incidence of fever,fatigue,chest tightness,consciousness disor-der,hyperglycemia,coagulation dysfunction,myocardial injury,liver and kidney injury.Compared with NDM group,DM group showed more severe involvement in both lobes,a higher proportion of secondary fungal infections,the duration of severe illness lasted longer(all P＜0.05).The mortality rate in DM group(41.43％)was higher than that in NDM group(6.78％).Multivariate logistic regression analysis showed that chest tightness,impaired consciousness,and fungal infection were independent risk factors for the outcome of hospitalized elderly patients with type 2 diabetes mellitus and COVID-19.Conclusions Elderly patients with type 2 diabetes mellitus and COVID-19 have various clinical symptoms,many secondary infections,insidious inflammatory reactions,early onset,high incidence and high mortality of multiple or-gan dysfunction,which require early monitoring and management.Chest tightness,consciousness disorders,and fungal in-fections are independent risk factors for its prognosis.
维普
万方数据
