Vagus nerve stimulation(VNS),as an emerging treatment method,can significantly improve motor function in stroke patients by regulating brain networks and enhancing neural plasticity.The application of VNS in the re-habilitation treatment of ischemic stroke,whether invasive or non-invasive,can effectively improve the functional recovery of stroke patients.This article summarizes and analyzes the application and research progress of VNS in the rehabilitation treat-ment of ischemic stroke.