中国临床保健杂志2024,Vol.27Issue(6) :859-864.DOI:10.3969/J.issn.1672-6790.2024.06.029

膀胱癌原代细胞培养及其医学应用的研究进展

Research progress of bladder cancer primary cell culture and medical application

彭瑞鲜 杨武林
中国临床保健杂志2024,Vol.27Issue(6) :859-864.DOI:10.3969/J.issn.1672-6790.2024.06.029

膀胱癌原代细胞培养及其医学应用的研究进展

Research progress of bladder cancer primary cell culture and medical application

彭瑞鲜 1杨武林2
扫码查看

作者信息

  • 1. 中国科学院合肥肿瘤医院泌尿肿瘤中心,合肥 230031
  • 2. 中国科学院合肥物质科学研究院健康与医学技术研究所
  • 折叠

摘要

膀胱癌可以分为非肌层浸润性膀胱癌和肌层浸润性膀胱癌,其中肌层浸润性膀胱癌患者的复发率与病死率都相对较高.深入理解膀胱癌的发病机制,积极寻找有效的膀胱癌治疗方法具有重要意义.原代培养的细胞能较好地保留原有肿瘤组织的细胞特性,是基础医学研究的良好工具.这些细胞可以用于研究肿瘤的生物学特性、评估药物的疗效和安全性等,为寻找新的治疗策略提供基础.该文就膀胱癌的原代细胞培养方法和鉴别手段等进行综述,为探索膀胱癌发病机制和诊疗新手段提供新的途径和思路.

Abstract

Bladder cancer can be divided into non-muscle invasive bladder cancer and muscle-invasive bladder cancer.The recurrence rate and mortality rate of muscle-invasive bladder cancer are relatively high.It is of great signifi-cance to deeply understand the pathogenesis and actively find effective treatment methods for bladder cancer.The prima-ry cultured tumor cells can better retain the cell characteristics of the original tumor tissue,which is a good tool for basic medical research.The primary tumor cells can be used to study the biological characteristics of tumors,evaluate the effi-cacy and safety of drugs,etc.,and provide a basis for the development of new therapeutic strategies.This article reviews the primary tumor cell culture and identification methods for bladder cancer,to provide new ways and ideas for the explo-ration of the pathogenesis of bladder cancer and the development of new diagnosis and treatment methods.

关键词

膀胱肿瘤/原代细胞培养/诊断,鉴别/生物疗法/综述

Key words

Urinary bladder neoplasms/Primary cell culture/Diagnosis,differential/Biological therapy/Review

引用本文复制引用

出版年

2024
中国临床保健杂志
卫生部北京医院 安徽省保健委员会

中国临床保健杂志

CSTPCD
影响因子:0.931
ISSN:1672-6790
段落导航相关论文