首页|环境新污染物影响胚胎发育的毒作用机制探索

环境新污染物影响胚胎发育的毒作用机制探索

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环境新污染物的健康风险目前受到高度关注,越来越多的证据表明多种环境新污染物母体暴露干扰胚胎发育。由于毒作用机制尚不明确,这限制了对环境新污染物发育毒性的风险评估及防治。本专栏中多篇文章利用动物模型、大数据分析以及单细胞测序等技术手段,对多种环境新污染物干扰胚胎发育的分子机制进行研究并做出综述。希望此专栏能促进对环境新污染物发育毒性毒作用机制的探索,并为相关政策制定提供参考。
Exploration of developmental toxicity mechanism of emerging environmental contaminants
The health risk posed by emerging environmental contaminants has become a public con-cern.Increasing evidence indicate that maternal exposure to multiple emerging environmental contaminants disrupts embryonic development.However,the underlying mechanisms of this de-velopmental toxicity remain unclear,hindering risk assessment and prevention efforts.In this column,the developmental toxicity mechanisms of various emerging pollutants were studied by employing model animals,big data analysis,and single-cell sequencing.We hope that this column will encourage further research into the developmental toxicity mechanisms of emerging envi-ronmental contaminants and provide a scientific base for policy-making.

emerging environmental contaminantdevelopmental toxicitymolecular mechanism

陈涛、张蕴晖

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苏州大学公共卫生学院,江苏 苏州 215123

复旦大学公共卫生学院/公共卫生安全教育部重点实验室,上海 200032

环境新污染物 发育毒性 分子机制

2024

环境与职业医学
上海市疾病预防控制中心 中华预防医学会

环境与职业医学

CSTPCD北大核心
影响因子:0.71
ISSN:1006-3617
年,卷(期):2024.41(12)