环境新污染物影响胚胎发育的毒作用机制探索
Exploration of developmental toxicity mechanism of emerging environmental contaminants
陈涛 1张蕴晖2
作者信息
- 1. 苏州大学公共卫生学院,江苏 苏州 215123
- 2. 复旦大学公共卫生学院/公共卫生安全教育部重点实验室,上海 200032
- 折叠
摘要
环境新污染物的健康风险目前受到高度关注,越来越多的证据表明多种环境新污染物母体暴露干扰胚胎发育.由于毒作用机制尚不明确,这限制了对环境新污染物发育毒性的风险评估及防治.本专栏中多篇文章利用动物模型、大数据分析以及单细胞测序等技术手段,对多种环境新污染物干扰胚胎发育的分子机制进行研究并做出综述.希望此专栏能促进对环境新污染物发育毒性毒作用机制的探索,并为相关政策制定提供参考.
Abstract
The health risk posed by emerging environmental contaminants has become a public con-cern.Increasing evidence indicate that maternal exposure to multiple emerging environmental contaminants disrupts embryonic development.However,the underlying mechanisms of this de-velopmental toxicity remain unclear,hindering risk assessment and prevention efforts.In this column,the developmental toxicity mechanisms of various emerging pollutants were studied by employing model animals,big data analysis,and single-cell sequencing.We hope that this column will encourage further research into the developmental toxicity mechanisms of emerging envi-ronmental contaminants and provide a scientific base for policy-making.
关键词
环境新污染物/发育毒性/分子机制Key words
emerging environmental contaminant/developmental toxicity/molecular mechanism引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据