The Correlation Between Vaginal Microecological Environment Changes And Premature Rupture Of Membranes During Pregnancy
Objective:To explore the correlation between vaginal microecological changes in late pregnancy wom-en with premature rupture of membranes and normal women through comparative analysis of vaginal microecological changes in late pregnancy women and the outcome of premature rupture of membranes,in order to prevent and reduce fe-tal membranes.Premature rupture provides basic research information.Methods:60 pregnant women who met the inclu-sion criteria from April 2022 to December 2023 were randomly collected and divided into premature rupture of mem-branes group(experimental group)and normal pregnant women group(control group)(n=30).Use the vaginitis com-bined detection kit(dry chemical enzymatic method)to detect the microecology of vaginal secretions,conduct a compre-hensive evaluation of the vaginal microecology,and compare the differences between the two groups.Results:The test group had mostly vaginal flora density and diversity levels Ⅰand Ⅳ,and the vaginal flora had an abnormal proportion of dominant bacteria and a positive probability of pathogens,pH≥4.5,positive hydrogen peroxide,positive β-glucuroni-dase,and acetaminophen.The positive proportion of glucosidase was higher than that of the control group,and the differ-ence was statistically significant(P<0.05).The positive incidence rate of sialidase in the test group was higher than that of the control group,but the difference was not statistically significant(P>0.05).Conclusion:The imbalance of vaginal microecology during pregnancy increases the chance of premature rupture of membranes,thereby increasing the chance of adverse outcomes in mother and baby.
vaginal microecologypremature rupture of membranes