Analysis of Cervical Conization Characteristics And Prognostic Factors In CIN Patients
Objective:To analyze the factors related to cervical conization characteristics,postoperative lesion re-siduals,and HPV clearance in patients with Cervical Intraepithelial Neoplasia(CIN).Methods:A bicentric retrospec-tive study was conducted,analyzing the basic information,HPV status,cervical conization surgery characteristics,and postoperative outcomes of 507 CIN patients.Results:The mean age of the patients was 41.69±9.35 years,with LEEP be-ing the primary surgery(86.59%).The postoperative lesion residual rate was 7.89%.Multivariate logistic regression anal-ysis revealed significant associations between lesion residuals and factors such as age,menopausal,preoperative tissue biopsy,cone depth,margins,gland involvement,and preoperative multiple HPV infections(P<0.05).Similarly,cone height,gland involvement,preoperative multiple HPV and high-risk HPV were significantly related to HPV clearance(P<0.05).Conclusion:Factors like gland involvement and preoperative multiple HPV infections are associated with the residuals of lesions post-cervical conization surgery and HPV clearance in CIN patients,providing valuable insights in developing personalized treatment plans.
NETL
NSTL
万方数据
维普
