Distribution and Drug Resistance of Pathogens in Blood Culture in Emergency De-partment
Objective:To analyze the distribution and drug sensitivity of pathogens in blood culture in emergency department,and to guide rational drug use of antibiotics in emergency department.Methods:The distribution and drug sensitivity results of blood culture positive pathogens in emergency department of Sun Yat-sen Memorial Hospital from January 1,2021 to December 31,2023 were retrospectively analyzed.Results:The top five bacteria were Escherichia coli(32.75%),Klebsiella pneumoniae(12.89%),Staphylococcus hominis(7.32%),Staphylococcus aureus(7.32%),and Staphylococcus epidermidis(5.05%).Staphylococcus aureus,Staphylococcus hominis,Staphylococcus epidermi-dis,Staphylococcus capitis,and Staphylococcus haemolyticus all had high resistance rates to penicillin G.Klebsiella pneumoniae had high resistance rates to ticarcillin/clavulanic acid,aztreonam,tobramycin,ciprofloxacin,and doxycy-cline.Proteus mirabilis had high resistance rates to minocycline.Enterobacter cloacae had high resistance rates to amoxi-cillin/clavulanic acid and cefoxitin.Conclusion:The pathogenic bacteria isolated from blood culture in the emergency department of our hospital are mainly Gram negative bacteria,with Escherichia coli being the main isolated bacteria;Escherichia coli,Klebsiella pneumoniae,Proteus mirabilis,and Acinetobacter baumannii are sensitive to carbapenems.