摘要
目的:探讨肝硬化患者治疗效果的影响因素.方法:选取2023年4月-2024年4月入院的肝硬化患者为研究对象,采用logistics回归分析肝硬化患者预后的独立影响因素,再采用结构方程模型绘制各因素之间作用的路径图.结果:共纳入研究对象190例,与治疗前相比,治疗后AST值、ALT值均显著下降(P<0.05).男性、低龄、超重、病程长、低学历、吸烟、饮酒、抑郁、焦虑等是治疗后ALT>40 U/L和AST>40 U/L的危险因素.结构方程模型发现,人口特征、行为疾病、心理因素均对治疗效果(AST或ALT降低)产生影响,以人口特征影响最大.结论:肝硬化患者治疗效果受多种因素的影响,临床上应采用个性化的治疗和护理方法.
Abstract
Objective:To Explore the influencing factors of treatment efficacy in patients with liver cirrhosis.Methods:Liver cirrhosis patients admitted from April 2023 to April 2024 as the research subjects were collected.Logis-tic regression was used to analyze the independent prognostic factors of liver cirrhosis patients.A structural equation mod-eling was constructed and a path diagram of the interactions between various factors was drown.Results:A total of 190 study subjects were included,and compared with before treatment,the level of AST and ALT significantly decreased af-ter treatment(P<0.05).Male,young age,overweight,long disease course,low education,smoking,drinking,depres-sion,and anxiety were risk factors for ALT>40 U/L and AST>40 U/L after treatment.The structural equation model found that demographic characteristics,behavioral disorders,and psychological factors all have an impact on treatment outcomes(reduced AST or ALT),with demographic characteristics having the greatest impact.Conclusion:The treat-ment effect of liver cirrhosis patients was influenced by various factors,and personalized treatment and nursing methods should be adopted in clinical practice.
维普
万方数据