Analysis of clinical features and incidence of meconium inhalation syndrome in new-borns with prolonged hospital stay at 2 years old
Objective:To explore the clinical features of meconium aspiration syndrome(MAS)in newborns and their disease status within 2 years after birth,providing insights for clinical disease management.Methods:A retrospec-tive review was conducted on clinical data of 87 cases of MAS newborns admitted from June 2016 to May 2021 and their disease status at 2 years post-discharge.The cases were divided into>7 days group(42 cases)and≤7 days group(45 cases).A comparison was made between the two groups in terms of in-hospital data and disease status within 2 years.Re-sults:In comparison to the≤7 days group,the>7 days group showed significantly higher hospitalization costs,inci-dence of neonatal asphyxia,air leak during hospitalization,proportion of high-frequency ventilator and invasive ventila-tor assistance,higher white blood cell count on the first day,higher incidence of platelet decrease,higher mean platelet volume on the 7th day,longer initial FiO2,admission 1-hour FiO2,total oxygen therapy duration,and total antibiotic use duration(P<0.05).Comparison of disease status within 2 years:The>7 days group had a higher number of wheez-ing cases than the≤7 days group,with a significant difference(P<0.05).Conclusion:Nearly half of MAS newborns ex-perienced prolonged hospital stays and increased hospitalization costs.Prolonged hospitalization in MAS newborns is asso-ciated with asphyxia,air leak,invasive ventilator assistance,and infection.MAS infants with extended hospital stays are more prone to wheezing within 2 years postpartum.
Length of hospital stayMeconium aspiration syndromeClinical featuresComplications
万方数据
维普
