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回顾性分析脓毒症患者继发消化道出血的危险因素

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目的:本研究旨在分析脓毒症患者继发消化道出血(Gastrointestinal Bleeding,GIB)的危险因素.方法:回顾性分析2022年1月至2023年12月期间中山大学孙逸仙纪念医院急诊重症监护病房(EICU)收治的154例脓毒症患者的临床资料,根据是否发生GIB分为两组:脓毒症继发GIB组(n=14)和脓毒症对照组(n=140).比较两组患者的临床资料,并运用Logistic回归分析确定危险因素.结果:与脓毒症对照组相比,脓毒症继发GIB组患者的GIB病史、肝硬化病史、住院期间使用糖皮质激素、阿司匹林、纤维蛋白原、未成熟网织红细胞比率(Immature Reticulocyte Fraction,IRF)均显著升高.多因素Logistic回归分析表明住院期间使用阿司匹林、GIB病史、IRF升高为脓毒症继发GIB的独立危险因素.结论:使用阿司匹林、GIB病史、IRF升高均为脓毒症继发GIB的独立危险因素.
Retrospective Analysis of the Risk Factors for Secondary Gastrointestinal Bleeding in Sepsis Patients
Objective:This study aimed to analyze the risk factors for secondary gastrointestinal bleeding(GIB)in patients with sepsis.Methods:A retrospective analysis was conducted on the clinical data of 154 patients with sepsis ad-mitted to the Emergency Intensive Care Unit(EICU)of Sun Yat-sen Memorial Hospital of Sun Yat-sen University from January 2022 to December 2023.Patients were divided into two groups based on the occurrence of GIB:the sepsis with secondary GIB group(n=14)and the sepsis control group(n=140).Clinical data of the two groups were compared,and logistic regression analysis was used to identify risk factors.Results:Compared with the sepsis control group,patients in the sepsis with secondary GIB group had significantly higher rates of GIB history,liver cirrhosis history,in-hospital use of glucocorticoids,aspirin,fibrinogen,and immature reticulocyte fraction(IRF).Multivariate logistic regression analysis indicated that in-hospital use of aspirin,GIB history,and elevated IRF were independent risk factors for secondary GIB in sepsis.Conclusion:The use of aspirin,GIB history,and elevated IRF are all independent risk factors for secondary GIB in sepsis.

sepsisgastrointestinal bleedingrisk factorsimmature reticulocyte fraction

黎童、方向韶、王鹏飞

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中山大学孙逸仙纪念医院急诊科(510120)

脓毒症 消化道出血 危险因素 未成熟网织红细胞比率

2024

岭南急诊医学杂志
广东省医学会

岭南急诊医学杂志

影响因子:0.437
ISSN:1671-301X
年,卷(期):2024.29(5)