Analysis of Clinical Characteristics During the Treatment Phase of 102 Patients with Hemorrhagic Fever with Renal Syndrome
Objective:To provide guidance for early correct diagnosis and assessment of disease severity by analyz-ing the epidemiological characteristics and clinical features of patients with Hemorrhagic Fever with Renal Syndrome(HFRS).Method:Analyzing the clinical data of patients diagnosed with HFRS admitted to Sun Yat-sen Memorial Hos-pital of Sun Yat-sen University from January 1997 to July 2023.Results:The study included 102 HFRS patients,with 82 males and 20 females,and an average age of 43.12±13.10 years.There were 63 cases with onset in spring and win-ter,and 58 cases with a history of suspected rodent contact.Three patients died,and the rest improved;only 8 cases presented with typical'three reds and three pains'symptoms,with an initial diagnosis accuracy of only 40.20%.Among the 102 patients,there were 37 cases of mild,38 cases of moderate,16 cases of severe,and 11 cases of critical illness.The degree of abnormality in initial tests such as creatinine,urea nitrogen,platelet count,coagulation function,and concurrent fluid accumulation was significantly higher in severe and critically ill patients compared to mild and moderate cases.Conclusion:The clinical symptoms of HFRS patients are diverse,with a low initial diagnosis accuracy.Emer-gency physicians should pay attention to multi-system symptoms and signs when encountering patients with unexplained fever,focus on liver and kidney function as well as coagulation indicators,and,if necessary,perform HFRS antibody tests for accurate diagnosis and timely treatment.
hemorrhagic fever with renal syndromeepidemiological characteristicsclinical featuresseverity level