Individuals with major depressive disorder(MDD)have been found to expend less physical and cognitive effort in effort-cost decision-making(ECDM)compared to the healthy.Factors related to the mo-tivational deficit in MDD could be other mental disorders and anticipatory or consummatory anhedonia.Furthermore,low reward reactivity and insufficient cognitive control may be the mechanism underlying the motivational deficit in MDD.Future research is needed to further investigate the ECDM deficit based on cognitive effort to explore the neural mechanism from the perspective of brain network and computa-tional model and focus on the motivational intervention in MDD.
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