Objectives To investigate the prognostic value of peak oxygen consumption(Peak VO2)for adverse outcomes in the Chinese coronary artery disease(CAD)population.Methods The study included CAD patients who underwent cardiopulmonary exercise tests(CPET)at Guangdong Provincial People's Hospital from January 2013 to April 2022.Patients were categorized into Q1-Q4 groups based on the quartile range of Peak VO2,and a multivariate Cox regression was employed for risk analysis.Restricted cubic spline(RCS)plots were used to assess the overall trend of the relation-ship between Peak VO2 and adverse outcomes.Results A total of 635 patients were included,with an average age of(59.57±11.09)years and a mean Peak VO2 of(19.66±5.38)mL·kg-1·min-1.Over approximately 3.4 years,there were 2.5%all-cause mortality,1.9%cardiovascular disease mortality,and 14.5%major adverse cardiovascular events(MACE).The three risk categories of Q4,Q3,Q2 demonstrated lower risks compared to Q1.RCS curves indicated a substantial initial decrease followed by a stabilization in the risk of all-cause mortality as Peak VO2 increased.Conclusions Peak VO2 has significant predictive value for adverse outcomes in Chinese CAD population.
关键词
冠状动脉疾病/峰值摄氧量/不良预后/心肺运动试验
Key words
coronary artery disease/peak oxygen consumption/adverse outcomes/cardiopulmonary exercise test
维普
万方数据