Objectives To analyze the value of 4-dimensional 4D ultrasound in the diagnosis of fetal cardiac malformations.Methods One hundred pregnant women who underwent prenatal examination and frequent postnatal follow-up diagnosis of fetal cardiac malformation from January 2019 to October 2022 in Puning Maternal and Child Health and Family Plan-ning Service Center were retrospectively selected as study subjects.The accuracy,misdiagnosis and leakage rates of fetal cardiac malformations diagnosed by conventional 2-dimensional(2D)ultrasound and 4D ultrasound spatio-temporal image correlation(STIC)techniques were compared,and the durations of 2D and 4D ultrasound examinations of individual pregnant women were recorded.Results Among the 100 fetuses with cardiac anomalies,ventricular septal defect was the most common,accounting for 39%of cases.Using postnatal follow-up as the"gold standard",we found that the diagnostic accuracy of conventional 2D ultrasound for fetal cardiac anomalies was 81.00%,which was lower than that of 4D ultrasound STIC(97.00%),while the rates of missed diagnosis and misdiagnosis were 11.00%and 8.00%,respectively,which were higher than those of 4D ultrasound STIC(2.00%and 1.00%)with statistically significant differences(P<0.05).And the mean duration of 2D ultrasound was significantly longer than that of 4D ultrasound in individual pregnant women,with a statistically significant difference[(5.23±0.81)min vs.(4.16±0.77)min,t=9.574,P<0.001)].Conclusions The 4D ultrasound STIC technique can objectively and clearly display the fetal heart anatomy,improve the accuracy of fetal heart malformation diagnosis,reduce the risk of misdiagnosis and missed diagnosis,and further improve the efficiency of prenatal screening,which can be an effective supplement to 2D ultrasound examination.
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