岭南心血管病杂志2024,Vol.30Issue(6) :587-591.DOI:10.3969/j.issn.1007-9688.2024.06.04

年龄和ACEF-rSS评分对冠状动脉疾病患者冠状动脉旁路移植术后主要不良心血管和脑血管事件的预测价值

Predictive Value of Age and ACEF-rSS Score for Major Adverse Cardiovascular and Cerebrovascular Events in Patients with Coronary Artery Disease After Coronary Artery Bypass Grafting

朱昌国 孟昭昀
岭南心血管病杂志2024,Vol.30Issue(6) :587-591.DOI:10.3969/j.issn.1007-9688.2024.06.04

年龄和ACEF-rSS评分对冠状动脉疾病患者冠状动脉旁路移植术后主要不良心血管和脑血管事件的预测价值

Predictive Value of Age and ACEF-rSS Score for Major Adverse Cardiovascular and Cerebrovascular Events in Patients with Coronary Artery Disease After Coronary Artery Bypass Grafting

朱昌国 1孟昭昀1
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作者信息

  • 1. 济南市人民医院全科医学科,济南 271100
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摘要

目的 明确年龄和年龄-肌酐-射血分数-残余SYNTAX分数(age-creatinine-ejection fraction,and residual SYNTAX score,ACEF-rSS评分)对冠状动脉粥样硬化性心脏病(coronary artery disease,CAD)患者冠状动脉旁路移植术后(coronary artery bypass graft,CABG)主要不良心血管和脑血管事件(major adverse cardiovascular and cere-brovascular events,MACCE)发生的预测价值.方法 回顾性分析济南市人民医院2008年1月至2018年5月期间接受CABG的572例CAD患者的临床资料,根据随访期内是否发生MACCE将患者分为MACCE组和对照组,对比两组患者的年龄、性别、ACEF-rSS评分等临床资料,使用多因素Cox回归模型评估年龄和ACEF-rSS评分导致CAD患者CABG术后MACCE发生的风险比,评价不同年龄和ACEF-rSS评分患者间的生存差异.结果 ACEF-rSS评分(≥1.061分)(HR=1.721,95%CI:1.127~2.629,P=0.012)、年龄(≥61岁)(HR=1.657,95%CI:1.043~1.631,P=0.032)是CAD患者CABG术后MACCE发生的独立危险因素.年龄≥61岁患者生存率低于年龄<61岁患者,差异有统计学意义(P<0.001).ACEF-rSS评分≥1.061分患者生存率低于ACEF-rSS评分<1.061分的患者,差异有统计学意义(P<0.001).结论 ACEF-rSS评分(≥1.061分)和年龄(≥61岁)是CAD患者CABG术后MACCE发生的危险因素.

Abstract

Objectives To clarify the predictive value of age,age-creatinine-ejection fraction,and residual SYNTAX score(ACEF-rSS)for the occurrence of major adverse cardiovascular and cerebrovascular events(MACCE)in patients with coronary artery disease(CAD)after coronary artery bypass grafting(CABG).Methods The clinical data of 572 CAD patients who underwent CABG in Jinan People's Hospital between January 2008 and May 2018 were retrospectively analyzed.The patients were divided into MACCE group and control group according to whether MACCE occurred during the follow-up period.The clinical data such as age,gender,and ACEF-rSS score of the patients between the two groups were compared,and a multifactorial Cox regression model was used to assess the differences in age and ACEF-rSS score resulted in the risk ratio of MACCE occurrence after CABG in CAD patients.The survival differences of patients between different ages and ACEF-rSS scores were evaluated.Results ACEF-rSS score(≥1.061 points)(HR=1.721,95%CI:1.127-2.629,P=0.012)and age(≥61 years)(HR=1.657,95%CI:1.043-1.631,P=0.032)were independent risk factors for the development of MACCE after CABG in CAD patients.The survival rate was significantly lower in patients aged≥61 years than in patients aged<61 years(P<0.001).The survival rate was significantly lower in patients with ACEF-rSS score≥1.061 than in patients with ACEF-rSS score<1.061(P<0.001).Conclusions ACEF-rSS score(≥1.061 scores)and age(≥61 years)are risk factors for the development of MACCE after CABG in CAD patients.

关键词

冠状动脉疾病/冠状动脉旁路移植术/主要不良心血管和脑血管事件/年龄-肌酐-射血分数-残余SYNTAX分数

Key words

coronary artery disease/coronary artery bypass grafting/major adverse cardiovascular and cerebrovascular events/age-creatinine-ejection fraction,and residual SYNTAX score

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出版年

2024
岭南心血管病杂志
广东省心血管病研究所

岭南心血管病杂志

CSTPCD
影响因子:0.872
ISSN:1007-9688
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