岭南心血管病杂志2024,Vol.30Issue(6) :592-597.DOI:10.3969/j.issn.1007-9688.2024.06.05

导管射频消融术治疗非缺血性心肌病室性心动过速患者的长期疗效分析:单中心经验

Long-Term Outcomes of Radiofrequency Ablation for Patients with Non-Ischemic Cardiomyopathy and Ventricular Tachycardia:A Single-Center Experience

廖江延 张佳媛 刘方舟 廖洪涛 方咸宏 邓海 薛玉梅 詹贤章
岭南心血管病杂志2024,Vol.30Issue(6) :592-597.DOI:10.3969/j.issn.1007-9688.2024.06.05

导管射频消融术治疗非缺血性心肌病室性心动过速患者的长期疗效分析:单中心经验

Long-Term Outcomes of Radiofrequency Ablation for Patients with Non-Ischemic Cardiomyopathy and Ventricular Tachycardia:A Single-Center Experience

廖江延 1张佳媛 1刘方舟 1廖洪涛 1方咸宏 1邓海 1薛玉梅 1詹贤章1
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作者信息

  • 1. 广东省心血管病研究所 南方医科大学附属广东省人民医院(广东省医学科学院)心内科,广州 510080
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摘要

目的 探索非缺血性心肌病(non-ischemic cardiomyopathy,NICM)合并室性心动过速(ventricular tachycar-dia,VT)患者行导管射频消融的长期疗效,分析影响疗效的因素.方法 本研究回顾性分析了2008年1月至2022年12月于广东省人民医院住院确诊为NICM-VT并行VT导管射频消融治疗的患者的临床资料.收集入选患者的临床基线数据、电生理资料及随访结果,采用单因素分析和多因素分析的方法分析影响长期疗效的因素.结果 纳入106例患者(男79例,女27例),年龄为(45.3±15.9)岁.经过33.2个月(中位随访时间)随访,39例患者VT复发,复发率为36.8%,8例死亡,病死率为7.5%.多因素回归分析显示年龄和VT种类≥3种是VT复发的独立危险因素(HR=1.040,95%CI:1.011~1.067,P=0.006;HR=2.623,95%CI:1.250~5.479,P=0.011),未提示消融途径是VT复发的独立危险因素.心力衰竭再入院是全因死亡的独立危险因素(HR=11.236,95%CI:1.728~73.074,P=0.011).结论 在经导管射频消融的NICM-VT患者中,术中VT种类≥3种、年龄是VT复发的独立危险因素,心力衰竭再入院是全因死亡的独立危险因素.

Abstract

Objectives To explore the long-term efficacy of radiofrequency catheter ablation in patients with non-ischemic cardiomyopathy(NICM)complicated with ventricular tachycardia(VT),and analyze the factors that affect the efficacy of radiofrequency catheter ablation.Methods This study retrospectively analyzed the clinical data of patients admitted to Guangdong Provincial People's Hospital from January 2008 to December 2022 who were diagnosed with NICM-VT combined with VT and underwent catheter radiofrequency ablation.The clinical baseline data,electrophysiological data and follow-up results of the enrolled patients were collected,and the factors affecting the long-term curative effect were analyzed by univariate analysis and multi-factor analysis.Results A total of 106 patients(79 males and 27 females)with an average age of(45.3±15.9)years were included.After a follow-up of 33.2 months(median follow-up time),39 patients had VT relapse,thus the recurrence rate was 36.8%;8 patients died,and the mortality rate was 7.5%.Multi-variate regression analysis showed that age and VT type≥3 were independent risk factors for VT recurrence(HR=1.040,95%CI:1.011-1.067,P=0.006;HR=2.623,95%CI:1.250-5.479,P=0.011),but did not suggest that ablation pathway was an independent risk factor for VT recurrence.Heart failure readmission was an independent risk factor for all-cause death(HR=11.236,95%CI:1.728-73.074,P=0.011).Conclusions In NICM-VT patients undergoing ra-diofrequency catheter ablation,age and≥3 types of VT during operation are independent risk factors for VT recurrence,and heart failure readmission is an independent risk factor for all-cause death.

关键词

非缺血性心肌病/室性心动过速/射频消融

Key words

non-ischemic cardiomyopathy/ventricular tachycardia/radiofrequency ablation

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出版年

2024
岭南心血管病杂志
广东省心血管病研究所

岭南心血管病杂志

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影响因子:0.872
ISSN:1007-9688
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