Influencing Factors of Major Adverse Cardiac and Cerebrovascular Event and Its Relationship with Basic Blood Pressure in Patients with Acute Myocardial Infarction After Percutaneous Coronary Intervention
Influencing Factors of Major Adverse Cardiac and Cerebrovascular Event and Its Relationship with Basic Blood Pressure in Patients with Acute Myocardial Infarction After Percutaneous Coronary Intervention
Objectives To investigate the influencing factors of major adverse cardiac and cerebrovascular event(MACCE)and its relationship with basic blood pressure in patients with acute myocardial infarction(AMI)after percuta-neous coronary intervention(PCI).Methods Clinical data of 291 patients with AMI after PCI were retrospectively chosen in the period from January 2014 to January 2020 in Tongchuan Mining Bureau Central Hospital.Patients were divided into different groups according to the baseline blood pressure level,the clinical data and the incidence of MACCE of different blood pressure level groups were compared.Cox regression model was used to evaluate the influencing factors of MACCE in AMI patients after PCI.Results There were significant differences in body mass index(BMI),proportion of essential hypertension,baseline heart rate level,concentration of high-density lipoprotein cholesterol(HDL-C)and the proportion of angiotensin converting enzyme inhibitors/angiotensin receptor blocker(ACEI/ARB)among different base-line blood pressure groups(P<0.05).There were significant differences in the total incidence of MACCE in different baseline blood pressure groups(P<0.05).The total incidence of MACCE in baseline blood pressure quartile 1 group was significantly higher than the other groups(P<0.05).Univariate and multivariate Cox regression analysis showed that age,Killip grade,ACEI/ARB,baseline systolic blood pressure≤106 mmHg(1 mmHg=0.133 kPa)or≥141 mmHg and baseline diastolic blood pressure≤63 mmHg or≥80 mmHg were independent risk factors for MACCE in patients with AMI after PCI(P<0.05).Conclusions The incidence of MACCE is closely related to age,Killip grade,ACEI/ARB and baseline blood pressure.The patients with baseline systolic blood pressure≤106 mmHg or≥141 mmHg and baselinediastolic blood pressure≤63 mmHg or≥80 mmHg possess higher risk of MACCE.
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