Objectives To evaluate the sensitivity,specificity,and safety of dipyridamole stress echocardiography contrast test(DIPSEC)in diagnosing coronary artery disease(CAD).Methods A total of 150 patients with clinically suspected CAD from January 2020 to December 2022 in Dongguan Kanghua Hospital were collected for DIPSEC examination to observe changes in ventricular wall motion and myocardial perfusion with positive finger tests showed reversible perfusion abnormalities with or without segmental ventricular wall motion abnormalities.Using coronary angiography(CAG)as the standard,coronary artery stenosis≥50%is considered positive,and the sensitivity and specificity of DIPSEC were calculated.Results The overall sensitivity and specificity of DIPSEC in diagnosing CAD were 98.1%and 90.6%,respectively.The sensitivity and specificity of the anterior descending branch,right coronary artery,and circumflex branch were 93.6%,89.1%,and 86.9%,respectively,and 97.5%,92.8%,and 84.7%,respectively.DIPSEC had a high sensitivity and specificity in diagnosing CAD as a whole.In patients with severe coronary artery stenosis,even in single vessel lesions,DIPSEC had high sensitivity and specificity.The incidence of adverse reactions was 20%during DIPSEC,with mild symptoms that could disappear after discontinuation of medication or administration of aminophyl-line,and no serious adverse reactions occurred.Conclusions DIPSEC diagnosis of CAD is safe and feasible.
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