首页|环泊酚在全身麻醉中应用的研究进展

环泊酚在全身麻醉中应用的研究进展

Research progress on application of ciprofol in general anesthesia

扫码查看
环泊酚是一种新型的静脉麻醉药,其在丙泊酚的结构基础上引入环丙基,形成了(R)-构型的异构体或小分子结构,从而提高了立体效应,增强了γ-氨基丁酸介导的氯离子内流,达到发挥镇静或麻醉的效果.环泊酚具有起效快、恢复快、效价高、镇静程度深、诱导成功率高等优势,已安全应用于内镜检查以及全身麻醉中.本文主要综述环泊酚在全身麻醉中的临床应用研究现状与进展.
Ciprofol is a novel intravenous anesthetic that introduces cyclopropyl based on the structure of pro-pofol,forming isomers or small molecule structures in the(R)-configuration,enhancing the stereo effect,and enhanc-ing the chloride ion influx mediated by gamma aminobutyric acid to exert sedative or anesthetic effects.It has the ad-vantages of fast onset,fast recovery,high potency,deep sedation,and high induction success rate.Currently,ciprofol has been safely used in endoscopic examination and general anesthesia.This article mainly describes the research sta-tus and clinical application of ciprofol in general anesthesia.

CiprofolGeneral anesthesia

杜晓媛、杨峻岭、郝在军

展开 >

内蒙古医科大学鄂尔多斯临床医学院,内蒙古鄂尔多斯 017000

鄂尔多斯市中心医院,内蒙古鄂尔多斯 017000

环泊酚 全身麻醉

2024

实用药物与临床
辽宁省药学会,中国医科大学附属盛京医院

实用药物与临床

CSTPCD
影响因子:1.633
ISSN:1673-0070
年,卷(期):2024.27(12)