Current situation analysis on combination of traditional Chinese medicine with West-ern medicine in polypharmacy of elderly patients with diabetes
Objective To analyze the current situation of combination use of Chinese medicine with Western medicine in polypharmacy of elderly patients with diabetes mellitus.Methods The medical records of elderly dia-betic patients discharged from the Internal Medicine Department of Xiangyang Central Hospital November 2023 were analyzed statistically,and the adverse impact of the combination of traditional Chinese medicine and Western medi-cines on polypharmacy for elderly diabetic patients was evaluated.Results A total of 1 014 patients were included in the study,including 771 patients(76.04%)with polypharmacy.Elderly patients with diabetes treated with combina-tion of traditional Chinese medicine with Western medicine were 462(45.56%),of which 59.84%were treated with traditional Chinese medicine for promoting blood circulation and removing blood stasis.Totally 83(10.77%)elderly patients with diabetes had 102 instances of inappropriate combination of traditional Chinese medicine with Western medicine.When Chinese medicine containing ingredients such as Licorice,Danshen/Sanqi,and Ginkgo biloba leaves were combined with Western medicine,adverse drug interactions were prone to occur.Among elderly diabetes patients with polypharmacy,there were 545 patients(70.69%)with 756 cases of potentially inappropriate medication(PIM),the most common drugs were insulin,clopidogrel,and eszopiclone.Conclusion It is common for elderly patients with diabetes to take traditional Chinese medicine.The combination of traditional Chinese medicine with Western medi-cine increases the rate of polypharmacy and PIM in elderly diabetic patients,resulting in bleeding,hypoglycemia,hypo-kalemia and other adverse reactions.The adverse drug interactions caused by inappropriate compatibility of Chinese medicine and Western medicine are easily overlooked.
Combination of traditional Chinese medicine with Western medicinePolypharmacyElderlyDiabe-tesDrug interactionPotentially inappropriate medication