The treatment plan of a patient with advanced colon cancer was adjusted from oral capecitabine to tegafur,gimeracil and oteracil potassium due to adverse reactions of hand-foot syndrome(HFS).After 4 days,due to the patient's inability to tolerate the adverse reactions of nausea and vomiting caused by tegafur,gimeracil and oteracil potassium,the drug was not used anymore.Considering the improvement of the patient's hand-foot syndrome,a re-duced dose of capecitabine was used after one month.Clinical pharmacists continuously monitored the changes in pa-tient's condition.After 6 cycles of chemotherapy,the patient experienced severe hand-foot syndrome again.Clinical pharmacists participated in MDT teams to optimize treatment plans,and provide pharmaceutical care to promote safe use of drugs in clinical practice.
关键词
手足综合征/替吉奥/卡培他滨/药学监护
Key words
Hand-foot syndrome/Tegafur,gimeracil and oteracil potassium/Capecitabine/Pharmaceutical care
维普
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