首页|基于AHP不同产地重楼药材的品质评价

基于AHP不同产地重楼药材的品质评价

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目的 对不同产地重楼药材进行科学全面的品质评价,为完善重楼药材的质量标准和筛选高品质药材提供理论依据。方法 收集24批次不同产地的重楼药材,按照《中华人民共和国药典》2020版要求考察其外观性状、显微、水分、总灰分和酸不溶性灰分;采用HPLC法测定重楼皂苷Ⅶ、Ⅱ、Ⅰ含量,应用AHP层次分析法从抗癌、抗炎药理功效为评分导向对其品质分析评价。结果 24批重楼药材的外观性状、水分、总灰分和酸不溶性灰分均符合规定;显微特征除云南省大理州云龙县白石镇重楼外,其余产地均符合要求;19批重楼药材的重楼皂苷Ⅰ、Ⅱ、Ⅶ总含量不少于0。6%;以抗癌、抗炎为评价导向,综合评分最高的重楼产地均为云南省大理白族自治州祥云县下庄村。结论 19批重楼药材符合《中华人民共和国药典》2020版要求,以云南省大理白族自治州祥云县下庄村的重楼品质最佳。
Quality Evaluation of Chonglou(Paridis Rhizoma)from Different Producing Areas Based on AHP
Objective The scientific and comprehensive quality evaluation of Chonglou(Paridis Rhizoma)from different producing areas was earried out to provide theoretical basis for improving the quality standard of Chonglou(Paridis Rhizoma)and screening high quality medicinal materials.Methods 24 batches of Chonglou(Paridis Rhizoma)from different origin were collected,and their appearance,microscopic,moisture,total ash and acid insoluble ash were investigated according to the requirements of 2020 edition Pharmacopoeia of the People's Republic of China.HPLC method was used to determine the contents of Ⅶ,Ⅱ and Ⅰ,and AHP was used to evaluate their quality based on their anti-cancer and anti-inflammatory pharmacological efficacy.Results The appearance,moisture,total ash content and acid insoluble ash content of 24 batches of Chonglou(Paridis Rhizoma)were in conformity with the regulations.The microscopic characteristics of all the producing areas met the requirements except Chonglou,Baishi town,Yunlong county,Dali prefecture,Yunnan province;The total content of Zonoside Ⅰ,Ⅱ and Ⅶ in 19 batches of Chonglou(Paridis Rhizoma)were not less than 0.6%;Based on the evaluation of anti-cancer and anti-inflammatory,the highest comprehensive scores of heavy buildings were all from Xiazhuang village,Xiangyun county,Dali Bai autonomous prefecture,Yunnan province.Conclusion 19 batches of Chonglou(Paridis Rhizoma)met the requirements of the 2020 edition Pharmacopoeia of the People's Republic of China,and the quality of was the best in Xiazhuang village,Xiangyun county,Dali Bai autonomous prefecture,Yunnan province.

Chonglou(Paridis Rhizoma)different originpolyphyllinanalytic hierarchy processquality evaluation

陈建辉、李娜、赵红玲、崔晓燕、于永洲、田雨轩、赵春颖、熊辉

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承德医学院,河北 承德 067000

河北省药品医疗器械检定研究院,河北 石家庄 050011

重楼药材 不同产地 重楼皂苷 层次分析法 品质评价

2025

辽宁中医药大学学报
辽宁中医药大学

辽宁中医药大学学报

影响因子:0.775
ISSN:1673-842X
年,卷(期):2025.27(1)