Exploration of the Association between Postmenopausal Knee Osteoarthritis and Sarcopenia Based on"Musculoskeletal Co-treatment"
Knee osteoarthritis(KOA)and sarcopenia(SP)represent two prevalent chronic musculoskeletal conditions among postmenopausal middle-aged and elderly women,characterized by a high disabling rate and frequent concurrent clinical manifestations.Nevertheless,the pathogenic mechanisms and pathological relationships between these two conditions remain largely elusive.This article reviews recent domestic and international literature on KOA and SP,highlighting that postmenopausal alterations in estrogen levels not only accelerate the progression of KOA,but also lead to diminished muscle strength and functionality.These conditions share multiple risk factors,such as obesity,vitamin D deficiency,and diabetes,with overlapping pathological processes.Additionally,fundamental theoretical research in traditional Chinese medicine(TCM)posits that kidney deficiency serves as a common pathogenesis for postmenopausal KOA and SP,with correlations in TCM symptoms and pattern-based treatment.The application of modern medical practices,TCM diagnosis and treatment,and evidence-based TCM research suggest that a holistic treatment and management approach can significantly alleviate symptoms and enhance the quality of life.In summary,the concept of"musculoskeletal co-treatment"is a pivotal academic guiding principle and therapeutic strategy that holds profound significance for the management and prevention of postmenopausal KOA and SP.However,further objective evidence is required to refine its precision,providing a reference for the targeted prevention and treatment of these conditions within TCM.
万方数据
