Research Progress of Classic Recipe Wenjing Decoction(温经汤)and Prediction Analysis of Quality Marker
The classic prescription Wenjing Decoction(温经汤)was published in Women's Complete Prescription.It has the effect of warming menstruation and tonifying deficiency,removing blood stasis and relieving pain.It is a common prescription for treating women with irregular menstruation,cold deficiency of blood sea and stagnation of Qi and blood.Clinical mainly used for dysmenorrhea,irregular menstruation,endometriosis and other female diseases.Through the analysis of its chemical composition,pharmacological action and modern clinical application,and based on the"five principles"of quality marker(Q-Marker),namely,quality transmission and traceability,component specificity,component and drug effect correlation,component measuability and compound compatibility environment,Q-Marker of Wenjing Decoction was predicted and analyzed.Ginsenosides Rg1,Re,Rb1,ferulic acid,paeonol,paeonol,paeonolide,paeonolide,cinnamic acid,ligusticolide,curcumenol,curcumendione,glycyrrhizin and glycyrrhizic acid were related to their drug efficacy,which could be used as Q-Marker for Wenjing Decoction,in order to provide reference for the subsequent establishment of a complete quality evaluation system for Wenjing Decoction.