固相萃取-气相色谱-三重四极杆串联质谱法测定水产品中丙泊酚和苯氧乙醇
Solid Phase Extraction Gas Chromatography Triple Quadrupole Tandem Mass Spectrometry Determination Propofol and Phenoxyethanol in Aquatic Products
万素琴 1王多娇 1周雪 1颜春荣 1徐春祥1
作者信息
- 1. 江苏省食品药品监督检验研究院,江苏 南京 210000
- 折叠
摘要
目的:建立固相萃取-气相色谱-三重四极杆串联质谱法测定水产品中丙泊酚、苯氧乙醇残留量的方法.方法:样品经提取后,通过固相萃取进行净化,采用DB-WAXUI色谱柱分离,检测模式为电子轰击离子源、动态多反应监测.结果:两种麻醉剂标准品线性检测范围为 10～500 ng·mL-1,检出限为 0.005 mg·kg-1;选取阴性样品进行加标回收试验,回收率为 87.5%～96.3%,相对标准偏差为 0.9%～7.3%.结论:该方法能够满足水产品麻醉剂残留检测的需要.
Abstract
Objective:To establish a method for the determination of propofol and phenoxyethanol residues in aquatic products by solid phase extraction-gas chromatography-triple quadrupole tandem mass spectrometry.Method:After extraction,the samples were purified by solid phase extraction and separated by DB-WAXUI chromatographic column.The detection mode was electron bombardment ion source and dynamic multi-reaction monitoring.Result:The linear detection range of the two anesthetic standards was 10～500 ng·mL-1,and the detection limit was 0.005 mg·kg-l.The recovery rate was 87.5%～96.3%,and the relative standard deviation was 0.9%～7.3%.Conclusion:This method can meet the needs of detection of anesthetic residues in aquatic products.
关键词
气相色谱-三重四极杆串联质谱法/水产品/鱼用麻醉剂/固相萃取Key words
triplequadrupole gas chromatography-mass spectrometry/aquatic products/fish anesthetics/solid phase extraction引用本文复制引用
基金项目
江苏省市场监督管理局科技项目(KJ2022066)
出版年
2024
NETL
NSTL
万方数据