维生素B12微囊粉的制备及稳定性研究
Preparation and Stability of Vitamin B12 Microcapsule Powder
陈礼宝 1张要华 1赵晨宇 1刘风莉 1赵锦慧1
作者信息
- 1. 郑州瑞普生物工程有限公司,河南 郑州 450001
- 折叠
摘要
以辛烯基琥珀酸淀粉钠为微囊壁材制备维生素B12 固体微囊粉,通过单因素试验优化制备条件,并通过储藏实验探究维生素B12 固体微囊粉的稳定性.结果显示,维生素B12 微囊粉的最佳制备条件为辛烯基琥珀酸淀粉钠占比 80%、壁材溶液pH值 5～6、剪切时间 11 min、均质压力 30 MPa,此条件下制得的 1%维生素B12 微囊粉有效成分含量保持在 0.97%以上.在储藏的 6 个月内,维生素B12 含量无显著变化,说明维生素B12 微囊粉具有良好的稳定性.
Abstract
The vitamin B12 microcapsule powder was constructed with sodium starch octenyl succinate as wall material,the preparation conditions were optimized by single factor test,and the stability of vitamin B12 solid microcapsule powder was investigated by storage experiment.The results showed that the optimal conditions for the preparation of vitamin B12 microcapsule powder were 80%sodium starch octenyl succinate,pH 5～6 of the wall solution,shear time of 11 min,homogenization pressure of 30 MPa,and the content of the active ingredients of the 1%vitamin B12 microcapsule powder was maintained at more than 0.97%under these conditions.There was no significant change in the vitamin B12 content during 6 months of storage,indicating that the vitamin B12 microencapsulated powder has good stability.
关键词
辛烯基琥珀酸淀粉钠/维生素B12/微胶囊/稳定性Key words
sodium starch octenyl succinate/vitamin B12/microcapsules/stability引用本文复制引用
出版年
2024
NETL
NSTL
万方数据