By measuring the size of inhibitory zone,it was verified that there was no antagonism between Bifidobacterium breve M-16V and Bifidobacterium longum subsp.infantis R0033.The two probiotics were combined and the probiotic drops containing M-16V and R0033 with 6 different carrier formulations were stored at 4℃and 25℃to explore their viable bacterial stability and antioxidant properties.It was found that after 24 months of storage,probiotic drops with MCT and single and double glycerol fatty acid ester as the carrier formula 1 have the highest viable bacteria count and stable acid value and peroxide value,which is suitable for the final formulation of probiotic drops.