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莱菔硫烷对脂毒性致肾损伤保护作用的研究进展

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莱菔硫烷(Sulforaphane,SFN)是一种天然的异硫氰酸盐类化合物,广泛存在于西兰花等十字花科蔬菜中,具有抗肿瘤、抗氧化、抗炎等多种生物活性.脂毒性导致的肾损伤是慢性肾病的重要原因,本文概括SFN对脂毒性致肾损伤的改善作用,为研究十字花科蔬菜防治肾损伤提供理论基础.
Research Advances in the Protective Effect of Sulforaphane on Renal Injury Induced by Lipid Toxicity
Sulforaphane(SFN)is a natural isothiocyanate compound that enriched in various cruciferous vegetables including broccoli,and exists multiple bioactivities including anti-cancer,anti-oxidant and anti-inflammtion.Lipotoxicity-induced renal injury is the main cause for chronic kidney disease.This article reviews the protective effect of SFN on lipotoxicity-induced renal injury and thus provides a theoretical basis for studying the prevention and treatment of kidney injury by cruciferous vegetables.

lipotoxicityrenal injurysulforaphanecruciferous vegetables

张春梅、伍春婷、牙甫礼

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大理大学 公共卫生学院,云南 大理 671000

脂毒性 肾损伤 莱菔硫烷 十字花科蔬菜

2024年度云南省基础研究专项面上项目

202401AT070081

2024

现代食品
国家粮食储备局郑州科学研究设计院

现代食品

影响因子:0.169
ISSN:2096-5060
年,卷(期):2024.30(17)