Simultaneous Determination of Eight N-nitrosamines in Health Foods by QuEChERS-Gas Chromatography-Triple Quadrupole Mass Spectrometry
N-nitrosamines have strong carcinogenicity,and there are few reports on the determination of N-nitrosamine content in health food.This paper uses QuEChERS technology to extract and purify N-nitrosamines in health food,and uses gas chromatography-triple quadrupole mass spectrometer to analyze and test N-nitrosamine compounds.The QuEChERS-gas chromatography-triple quadrupole mass spectrometry method is established for the simultaneous determination of eight N-nitrosamines in health food.The experimental results show that the eight N-nitrosamine compounds have good linearity in the concentration range of 0.5 μg·L-1 to 10.0 μg·L-1,with linear correlation coefficients greater than 0.999.The detection limit is from 0.12 μg·g-1 to 0.32 μg·kg-1,and the quantification limit is from 0.40 μg·kg-1 to 1.08 μg·kg-1.The average spiked recovery rates of the three concentration levels is from 88.7%to 115.4%,and the relative standard deviation is from 2.0%to 9.5%.The method is used to determine ten kinds of common health food in the market,and eight kinds of N-nitrosamines are not detected.This method has the advantages of simple operation,small sampling amount,good sensitivity and precision,and is suitable for the determination of N-nitrosamines compounds in health foods.
N-nitrosaminehealth foodQuEChERSgas chromatography-triple quadrupole mass spectrometry
NETL
NSTL
万方数据
维普
