Objective To investigate the clinical and imaging manifestations,pathology and treatment of pituicytoma.Methods The clinical data,imaging findings,pathology and treatment of 2 patients who were diagnosed as pituicytoma in our hospital from January 2019 to October 2023 were retrospectively analyzed,and the relevant literature was reviewed.Results There were 2 patients of pituicytoma,1 male and 1 female.The main symptoms include headache and vision decreased,and the head magnetic resonance imaging showed iso-intense on T1 weighted imaging and hypo-or iso-intense on T2 weighted imaging in and above the sellar region,substantial le-sions were increased signal intensity after enhancement.Transnasal sphenoid approach under mi-croscope and neuroendoscope were performed respectively.The postoperative pathology was pi-tuicytoma(WHO Grade Ⅰ),which was not treated with radiotherapy.Two cases were followed up for 4 years and 3 months without recurrence.Conclusion Pituicytoma is rare and easily misdiag-nosed,the blood supply of tumor tissue is affluent,total surgical resection is the main way of treatment.