Assessment of the relationship between the distribution,location,and quantity of cerebral in-farction lesions and patent foramen ovale under resting state and Valsalva maneuver using carotid ar-tery ultrasound
Objective Analyze the relationship between the distribution,location,and quan-tity of cerebral infarction lesions and patent foramen ovale under resting state and Valsalva ma-neuver evaluated by carotid artery ultrasound.Methods A total of 137 stroke patients who visi-ted our hospital from January 2021 to December 2023 were selected as the research subjects.Based on the condition of patent foramen ovale(PFO),stroke patients were divided into PFO group(n=62)and no PFO group(n=75).During the same period,healthy subjects from the physical ex-amination department were selected as the control group(n=70),and the right to left shunt be-tween stroke patients and the healthy control group was analyzed under resting state and Valsalva action,Compare the distribution,location,and quantity of cerebral infarction foci between PFO and non PFO patients.Results There is a significant difference in the degree of right to left shunting between patients with cerebral infarction and the healthy control group under resting state and Valsalva action.At the same time,under Valsalva action,the degree of right to left shunting in patients with cerebral infarction is significantly increased compared to resting state.There are significant differences in the distribution,location,and quantity of cerebral infarction le-sions between PFO group patients and non PFO patients.PFO group patients have more posterior circulation supply areas,and the number of cerebral infarction lesions is mainly multiple(P<0.05).Conclusion There is a certain relationship between PFO and the distribution,location,and quantity of cerebral infarction foci.PFO related cerebral infarction foci are more widely distribu-ted and tend to occur in the posterior circulation,with a greater number.This may be related to multiple microemboli caused by right to left shunting,providing a basis for the prevention and treatment of PFO related cerebral infarction.