Key development direction is green renewable plasticizer instead of traditional petroleum base plasticizer. Tak-ing vegetable oils and waste grease as raw material, including epoxy soybean oil, epoxy fatty acid methyl esters, chloro-methoxy fatty acid methyl ester, preparation process, product characteristics and application status of environment-friendly plasticizer-swere discussed.And prospect of environment-friendly plasticizers based on oil and fat were predicted.