Landsat images of four periods (1977,1990,1997 and 2007) were used to extract the information of wetlands in the typical area of the Yangtze River source region.The dynamic changes of wetlands and its driving factors during 1977-2007 were analyzed.Meteorological data of 1971-2007 were used to analyze the climate change trends and characteristics of study area,and analyze the relevance of wetland change and climatic factors.The results indicated that,during 1977-2007,the total area of wetlands reduced by 37%.The quality of wetlands degenerated obviously,mainly in marsh and flood land transforming to grassland,bare land and sand land.The regional climate has been tending to warming and drying in recent 40 years and the temperature is the most important factor affecting the changes of wetlands in the study area.