Research Progress on the Intervention of Metabolic Associated Fatty Liver Disease with Compound Traditional Chinese Medicine
Metabolic associated fatty liver disease(MAFLD)has become a global health problem,so far,few drugs have been approved for marketing,and its complex pathogenesis has led to great challenges in drug development.In this paper,the current status of MAFLD drug research and development at home and abroad,as well as the clinical research and new drug development of compound Chinese medicine in the treatment of MAFLD were summarized.Through the basic research of compound Chinese medicine,it was found that compound Chinese medicine could improve lipid metabolism,reduce inflammation and fibrosis,and regulate intestinal microflora through comprehensive intervention of multi-target and multi-pathway regulation.It is suggested that compound Chinese medicine may be one of the potential new drug development fields for MAFLD treatment in the future.This article reviewed the intervention of metabolic-related fatty liver disease with compound traditional Chinese medicine,aiming to provide a reference for clinical practice.