Current Status and Prospects of Clinical Cure for Chronic Hepatitis B
Chronic hepatitis B is a progressive disease that leads to a significant number of deaths each year due to cirrhosis and hepatocellular carcinoma.In recent years,with the deepening understanding of the mechanisms of Hepatitis B virus infection,advance-ments in different transformation strategies for nucleos(t)ide analogs and long-acting interferons,and the development of new drugs,a cure for hepatitis B has become an achievable goal.This paper reviewed the concept of clinical cure for hepatitis B,its historical devel-opment,potential mechanisms,the current treatment landscape,and the latest progress in new drug development.The challenges encountered in the process of curing hepatitis B and directions for future efforts were also discussed,providing a reference for clinical research and practice.
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维普
