微创单通道经皮肾镜钬激光碎石术与体外冲击波碎石术治疗肾结石的临床效果比较
Comparison of the clinical efficacy of minimally invasive single channel percutaneous nephrolithotripsy with holmium laser and extracorporeal shock wave lithotripsy in the treatment of kidney stones
黄国健 1彭小勇1
作者信息
- 1. 广东省封开县人民医院 泌尿外科,广东 肇庆 526500
- 折叠
摘要
目的 探讨微创单通道经皮肾镜钬激光碎石术(percutaneous nephrolithotomy,PCNL)治疗肾结石的临床效果.方法 选取广东省封开县人民医院2021年1月至2023年6月收治的88例肾结石患者作为研究对象,采用随机数字表法分为对照组与观察组,每组44例.对照组行体外冲击波碎石术(extracorporeal shock-wave lithotripsy,ESWL)治疗,观察组行PCNL治疗.比较两组手术时间、肾功能[血尿素氮(blood urea nitrogen,BUN)、胱抑素C(cystatin,Cys C)、血肌酐(serum creatinine,Scr)、脂质运载蛋白(neutrophil gelatinase-associated lipocalin,NGAL)]、结石清除率及并发症发生情况.结果 观察组手术用时为(55.97±7.62)min,短于对照组的(63.65±9.48)min,清石率(97.73％)高于对照组(81.82％),并发症发生率(4.55％)低于对照组(20.45％),差异有统计学意义(P＜0.05).两组术前肾功能指标水平比较,差异无统计学意义(P＞0.05);观察组术后肾功能指标水平均低于对照组,差异有统计学意义(P＜0.05).结论 肾结石患者采用PCNL治疗效果优于ESWL,手术时间短、清石率高、并发症少,对患者肾功能影响小.
Abstract
Objective To explore the clinical efficacy of minimally invasive single channel percutaneous nephrolithotripsy with holmium laser(PCNL)in the treatment of kidney stones.Methods A total of 88 patients with kidney stones admitted to Fengkai Courty People's Hospital,Guangdong Province from January 2021 to June 2023 were selected as the study objects,and were divided into control group and observation group by random number table method,with 44 cases in each group.The control group received extracorporeal shock-wave lithotripsy(ESWL)treatment,while the observation group received PCNL treatment.The surgical time,renal function[blood urea nitrogen(BUN),cystation(Cys C),serum creatinine(Scr),neutrophil gelatinase-associated lipocalin(NGAL),stone clearance rate,and incidence of complications were compared between two groups.Results The surgical time of the observation group was(55.97±7.62)minutes,which was shorter than(63.65±9.48)minutes of the control group.The stone clearance rate of the observation group(97.73％)was higher than that of the control group(81.82％),and the incidence of complications(4.55％)was lower than that of the control group(20.45％).The differences were statistically significant(P＜0.05).There was no statistically significant difference in the levels of preoperative renal function indicators between the two groups(P＞0.05).The postoperative renal function indicators in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion PCNL treatment is more effective than ESWL in patients with kidney stones,with shorter surgical time,higher stone clearance rate,fewer complications,and minimal impact on renal function.
关键词
肾结石/钬激光碎石术/肾功能/并发症Key words
Kidney stones/Holmium laser lithotripsy/Renal function/Complications引用本文复制引用
出版年
2024
NETL
NSTL
万方数据