输尿管软镜与经皮肾镜碎石术在肾结石治疗中的对比研究
Comparative study of uretal flexible lithotripsy and percutaneous lithotripsy for kidney stones
向习文 1谭奎 2张旭 1杨春娇 1朱冠 1向凯 1严飞 1王永瑞1
作者信息
- 1. 建始县中医医院 外三科,湖北 恩施 445300
- 2. 建始县中医医院 麻醉科,湖北 恩施 445300
- 折叠
摘要
目的 对比观察输尿管软镜碎石术(retrograde intrarenal surgery,RIRS)与经皮肾镜碎石术(percutaneous nephrolithotomy,PCNL)在肾结石治疗中的应用效果.方法 选取2021年1-12月建始县中医医院收治的52例肾结石患者进行研究,按照不同手术方法分为观察组与对照组,每组26例.观察组行RIRS治疗,对照组行PCNL治疗.比较两组手术相关指标、应激反应指标、疼痛程度、舒适状况、肾功能、不良反应及清石率.结果 观察组手术下床活动、住院时间短于对照组,且术中出血量少于对照组,差异有统计学意义(P＜0.05);观察组应激反应指标低于对照组,差异有统计学意义(P＜0.05);观察组疼痛评分及不良反应低于对照组,且舒适度评分高于对照组,差异有统计学意义(P＜0.05);观察组血清胱抑制素C水平高于对照组,且尿肾脏损伤因子-1、中性粒细胞明胶酶相关载脂蛋白及血肌酐水平低于对照组,差异有统计学意义(P＜0.05);两组清石率比较,差异无统计学意义(P＞0.05).结论 RIRS具有更为显著的优势,可显著改善肾功能,减轻疼痛,缩短康复时间,且安全性更高.
Abstract
Objective To observe the effect of retrograde intrarenal surgery(RIRS)and percutaneous nephrolithotomy(PCNL)in the treatment of renal stones.Methods A total of 52 patients with kidney stones admitted to Jianshi County Hospital of Traditional Chinese Medicine from January to December 2021 were selected for study.According to different surgical methods,they were divided into observation group and control group,with 26 cases in each group.The observation group was treated with RIRS,and the control group was treated with PCNL.The operation related indicators,stress response indicators,pain degree,comfort status,renal function,adverse reactions and stone clearance rate were compared between the two groups.Results The observation group exhibited shorter postoperative bed rest and hospital stay durations compared to the control group,along with significantly reduced intraoperative blood loss(P＜0.05).The stress indicators of the observation group were lower than those of the control group,and the differences were statistically significant(P＜0.05).The observation group also experienced lower pain scores and fewer adverse reactions while reporting higher comfort scores compared to the control group(P＜0.05).Levels of serum C inhibitor of the observation group were higher than that of the control group.In the control group and urinary kidney injury factor-1,neutrophil gelatinase-related apolipoprotein and serum creatinine levels were lower than those in the control group(P＜0.05).Comparing the stone clearance rates between the two groups,the diflerence was not statistically significant(P＞0.05).Conclusions Flexible ureteroscopic lithotripsy has more significant advantages,which can significantly improve renal function,reduce pain,shorten recovery time,and has higher safety.
关键词
输尿管软镜碎石术/经皮肾镜碎石术/肾结石Key words
Flexible ureteral lithotripsy/Percutaneous nephrolithotripsy/Kidney stones引用本文复制引用
出版年
2024
NETL
NSTL
万方数据