泌尿外科杂志(电子版)2024,Vol.16Issue(3) :17-20.DOI:10.20020/j.CNKI.1674-7410.2024.03.04

输尿管软镜碎石术在2 cm左右肾结石中的应用价值

Application value of ureteral flexible lithotripsy with kidney stones about 2 cm

方晖东 刘俊峰 潘佐 乔璐 刘智超
泌尿外科杂志(电子版)2024,Vol.16Issue(3) :17-20.DOI:10.20020/j.CNKI.1674-7410.2024.03.04

输尿管软镜碎石术在2 cm左右肾结石中的应用价值

Application value of ureteral flexible lithotripsy with kidney stones about 2 cm

方晖东 1刘俊峰 1潘佐 1乔璐 1刘智超1
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作者信息

  • 1. 内蒙古自治区人民医院 泌尿外科,内蒙古 呼和浩特 010010
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摘要

目的 探讨输尿管软镜碎石术在2 cm左右肾结石患者碎石中的应用价值.方法 纳入2023年1月至2024年1月90例1.8~2.2 cm肾结石患者,取自内蒙古自治区人民医院.对全部临床资料开展回顾性分析,按照不同治疗方式分为对照组与研究组,每组45例.对照组采用微通道经皮肾镜激光碎石术治疗,研究组采用输尿管软镜碎石术治疗.比较两组手术、住院时间、术中出血量、治疗前后肾功能、应激指标、炎性因子指标、并发症发生率.结果 相比于对照组,研究组手术时间更长,住院时间更短,术中出血量更低,差异有统计学意义(P<0.05).两组治疗前血肌酐、血尿素氮、去甲肾上腺素、皮质醇对比,差异无统计学意义(P>0.05);治疗后2 d,两组血肌酐、血尿素氮、去甲肾上腺素、皮质醇高于治疗前,且研究组上述指标低于对照组,差异有统计学意义(P<0.05).两组治疗前C反应蛋白、白细胞介素-6、降钙素原比较,差异无统计学意义(P>0.05);两组治疗后2 d的C反应蛋白、白细胞介素-6、降钙素原均高于治疗前,且研究组上述指标低于对照组,差异有统计学意义(P<0.05).并发症总发生率相比,研究组低于对照组,差异有统计学意义(P<0.05).结论 1.8~2.2 cm肾结石患者采用输尿管软镜碎石术可缩短住院时间,降低出血量,改善应激反应,降低炎性因子、并发症发生率.

Abstract

Objective To evaluate the value of ureteral soft lithotripsy in patients with kidney stones about 2 cm.Methods Clinical data of 90 patients with 1.8-2.2 cm kidney stones admitted to the People's Hospital of Inner Mongolia Autonomous Region from January 2023 to January 2024 were retrospectively analyzed.According to different treatment methods,they were divided into control group and observation group,with 45 cases in each group.The control group was treated with microchannel percutaneous nephrolithotripsy and the observation group was treated with ureteral soft lithotripsy.Operation,hospital stay,intraoperative blood loss,renal function before and after treatment,stress index,inflammatory factor index and the incidence of complications was compared in both groups.Results Compared with the control group,the duration of hospital stay was shorter,and the bleeding rate decreased significantly in the treatment group(P<0.05).Before treatment,there was no significant difference in serum creatinine,blood urea nitrogen,norepinephrine and cortisol between the two groups(P>0.05).Two days after treatment,serum creatinine,blood urea nitrogen,norepinephrine and cortisol in 2 groups were higher than those before treatment,and there were significant differences between the two groups(P<0.05).Before treatment,there was no significant difference in C-reactive protein,interleukin-6 and procalcitonin between the two groups(P>0.05).Two days after treatment,C-reactive protein,interleukin-6 and procalcitonin in 2 groups were higher than those before treatment,and there were significant differences between the two groups(P<0.05).The rate of complications was significantly reduced in the observed group compared with the normal group(P<0.05).Conclusions Ureteral soft lithotripsy with 1.8-2.2 cm kidney stones can shorten the hospital stay,reduce the amount of blood loss,improve the stress response,and reduce the incidence of inflammatory factors and complications.

关键词

输尿管软镜碎石术/肾结石/应激/炎性因子

Key words

Ureteral soft lithotripsy/Kidney stones/Stress/Inflammatory factor

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出版年

2024
泌尿外科杂志(电子版)
人民卫生出版社

泌尿外科杂志(电子版)

影响因子:0.225
ISSN:1674-7410
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