Aim To investigate the effects of body mass index(BMI)on the outcome of intracytoplasmic sperm injection(ICSI)in infertility patients with polycystic ovary syndrome(PCOS).Methods 200 patients with ICSI assisted pregnancy,in-cluding 82 patients with PCOS and 118 patients without PCOS,were selected from the reproductive center of our hospital and divided into non-overweight group(BMI＜24 kg/m2)and overweight group(BMI≥24 kg/m2),according to body mass index.PCOS patients were divided into non-overweight group(47 cases)and overweight group(35 cases),whereas non-PCOS patients were divided into non-overweight group(81 cases)and overweight group(37 cases).The general clinical characteristics,gonadotropin(Gn)dosage,Gn time,oocyte number,mature oocyte,fertilization rate,embryo quality,pregnancy rate,implantation rate and abor-tion rate of the 4 groups were compared.Results The LH levels of overweight and non-overweight individuals in the PCOS group were higher than those in the non-PCOS group.The BMI of overweight individuals in both the PCOS and non-PCOS groups was high-er than that of non-overweight individuals(P＜0.05).Compared with the non-overweight subgroup in the same group,the overweight subgroup showed an increase in total Gn and a decrease in daily trigger E2 levels(P＜0.05).The total amount of Gn and daily trig-ger E2 levels were lower in PCOS super-recombination than in non-PCOS super-recombination;PCOS non-super-recombination was lower than non-PCOS non-super-recombination(P＜0.05).The number of follicles,number of retrieved eggs,and number of mature oocytes were higher in PCOS non-super-recombination than in non-PCOS non-super-recombination,and PCOS super-recombination was higher than in non-PCOS super-recombination(P＜0.05).Conclusion The increase of BMI will increase the dosage of gonado-tropin during ovulation,and the number of follicles and eggs obtained in patients with PCOS are higher than those without PCOS.
维普
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