Impact of body mass index on outcome of intracytoplasmic sperm injection in patients with PCOS
Aim To investigate the effects of body mass index(BMI)on the outcome of intracytoplasmic sperm injection(ICSI)in infertility patients with polycystic ovary syndrome(PCOS).Methods 200 patients with ICSI assisted pregnancy,in-cluding 82 patients with PCOS and 118 patients without PCOS,were selected from the reproductive center of our hospital and divided into non-overweight group(BMI＜24 kg/m2)and overweight group(BMI≥24 kg/m2),according to body mass index.PCOS patients were divided into non-overweight group(47 cases)and overweight group(35 cases),whereas non-PCOS patients were divided into non-overweight group(81 cases)and overweight group(37 cases).The general clinical characteristics,gonadotropin(Gn)dosage,Gn time,oocyte number,mature oocyte,fertilization rate,embryo quality,pregnancy rate,implantation rate and abor-tion rate of the 4 groups were compared.Results The LH levels of overweight and non-overweight individuals in the PCOS group were higher than those in the non-PCOS group.The BMI of overweight individuals in both the PCOS and non-PCOS groups was high-er than that of non-overweight individuals(P＜0.05).Compared with the non-overweight subgroup in the same group,the overweight subgroup showed an increase in total Gn and a decrease in daily trigger E2 levels(P＜0.05).The total amount of Gn and daily trig-ger E2 levels were lower in PCOS super-recombination than in non-PCOS super-recombination;PCOS non-super-recombination was lower than non-PCOS non-super-recombination(P＜0.05).The number of follicles,number of retrieved eggs,and number of mature oocytes were higher in PCOS non-super-recombination than in non-PCOS non-super-recombination,and PCOS super-recombination was higher than in non-PCOS super-recombination(P＜0.05).Conclusion The increase of BMI will increase the dosage of gonado-tropin during ovulation,and the number of follicles and eggs obtained in patients with PCOS are higher than those without PCOS.
万方数据
维普
