Predictive value of MHR in left atrial enlargement in patients with primary hypertension
Aim To explore the predictive value of monocyte to high density lipoprotein cholesterol ratio(MHR)for left at-rial enlargement in patients with primary hypertension(PHT).Methods 112 PHT patients in our hospital and 94 healthy indi-viduals were retrospectively selected as the PHT group and the control group respectively.According to whether LAE has occurred,PHT patients were divided into LAE group and non-LAE group.The clinical data,blood routine and biochemical indexes of control group and PHT group(including LAE group and non-LAE group)were compared.Left atrial volume(LAV)and left atrial volume index(LAVI)were calculated by chest echocardiography.Multivariate Logistic regression was used to analyze the risk factors of LAE in PHT patients,Pearson correlation was used to analyze the correlation between various indexes and LAE in PHT patients,and ROC curve was used to analyze the predictive value of MHR for LAE in primary PHT patients.Results Compared with the control group,the age,blood pressure,body mass index,white blood cell,neutrophil,monocyte,total cholesterol(TC),triglycerides(TG),low density lipoprotein cholesterol(LDLC),body surface area(BSA),LAV,LAVI,and MHR in the PHT group were in-creased(P<0.05).Compared with the non-LAE group,the MHR,monocyte,low density lipoprotein cholesterol(LDLC)of PHT patients in the LAE group were significantly higher,while high density lipoprotein cholesterol(HDLC)was decreased(P<0.05).The results of multivariate Logistic regression analysis showed that age,MHR,HDLC,LDLC,white blood cell,and monocyte were all risk factors for LAE in PHT.The correlation analysis results showed that MHR was positively correlated with age,BSA,white blood cell,LAV,and LAVI(P<0.05),and negatively correlated with TC,TG,and HDLC(P<0.05).The ROC curve results show that when the cut-off value is 0.42,MHR has good predictive value for LAE in PHT.Conclusion MHR has high predictive value for the occurrence of left atrial enlargement in PHT patients and has the potential as an independent predictor.
万方数据
维普
