The diagnostic value of ultrasound blood flow imaging and contrast enhanced ultrasound in colorectal cancer and their correlation with microvessel density of lesions
Aim To investigate the diagnostic value of ultrasound blood flow imaging and contrast enhanced ultrasound(CEUS)in colorectal cancer and its correlation with microvessel density(MVD)of lesions.Methods 107 patients with colorec-tal cancer were selected and divided into malignant group(subgroups according to stage)and benign group according to the pathologi-cal results.The peak systolic velocity(PSV),resistance index(RI),end diastolic velocity(EDV),peak intensity(PI),time to peak(TTP),area under the curve(AUC),and Slope rate of ascending curve(A)of CEUS were compared among the three groups.The correlation of ultrasound blood flow imaging,CEUS index and MVD in malignant group was analyzed.The diagnostic value of ul-trasound blood flow imaging and CEUS in colorectal cancer was analyzed.Results The accuracy of ultrasound blood flow imaging combined with CEUS was higher than that of single detection(P＜0.05).PSV and EDV in malignant group were higher than those in benign group,and RI was lower than that in benign group.PI and TTP were lower than those in benign group,while AUC and A were higher than those in benign group(P＜0.05).PSV,EDV and MVD in stage Ⅳ group were higher than those in stage Ⅰ-Ⅲgroup,and RI was lower than that in stage Ⅰ-Ⅲ group.PI and TTP in stage Ⅱ-Ⅳ group were lower than those in stage Ⅰ group,while AUC and A were higher than those in stage Ⅰ group(P＜0.05).In malignant group,PI and RI were negatively correlated with MVD,while AUC and PSV were positively correlated with MVD(P＜0.05).The diagnostic efficiency of ultrasound blood flow imaging combined with CEUS in colorectal cancer was higher than that of single detection(P＜0.001).Conclusion The diagnostic efficacy of ultrasound blood flow imaging combined with CEUS for colorectal cancer is better than that of single detection,which can reflect the microcirculation blood flow perfusion state of colorectal cancer,and provide reference for clinical treatment of colorectal cancer.
万方数据
维普
