Clinical value of cerebral blood flow ultrasound and ONSD for nerve function evaluation in CPR patients
Aim To explore clinical value of cerebral blood flow ultrasound combined with optic nerve sheath diameter(ONSD)for nerve function evaluation in patients undergoing cardio-pulmonary resuscitation(CPR).Methods A total of 100 patients with coma after CPR were enrolled.According to different prognosis results,they were divided into good prognosis group and poor prognosis group.The clinical data,postoperative cerebrospinal fluid pressure and ultrasound parameters at 1 d,3 d and 7 d after surgery were compared between the two groups.The correlation between CSF pressure and ultrasound parameters,influencing factors of prognosis,and evaluation value of ultrasound parameters for nerve function prognosis were analyzed.Results Compared with good prognosis group,CPR time and mechanical ventilation time were increased in poor prognosis group.Proportion of nosocomial cardiac arrest proportion was decreased,pulsative index(PI)and resistance index(RI)at 1 d after surgery,as well as ONSD,PI and RI at 3 d and 7 d after surgery,were increased.Mean flow velocity(Vm)at 1 d after surgery,and peak systolic velocity(Vs),end diastolic velocity(Vd)and Vm at 3 d and 7 d after surgery,were decreased.And postoperative postoperative cerebrospinal fluid pressure was increased(P＜0.05).The postoperative postoperative cerebrospinal fluid pressure was correlated with ONSD,RI,PI and Vm(P＜0.05).CPR time,postoperative cerebrospinal fluid pressure,ONSD,RI,PI and Vm were independent risk factors for nerve function prognosis(P＜0.05).Bilateral ONSD,Vm,RI and PI at 3 d after surgery were of good predictive value for nerve function prognosis of CPR patients(P＜0.05).Conclusion The dynamic monitoring of cerebral blood flow ultrasound and ONSD can effectively evaluate the prognosis of nerve function in coma patients after CPR.
cerebral hemodynamicsoptic nerve sheath diametercardio-pulmonary resuscitationnerve function
万方数据
维普
